simDNAmixtures - Simulate Forensic DNA Mixtures

Mixed DNA profiles can be sampled according to models for probabilistic genotyping. Peak height variability is modelled using a log normal distribution or a gamma distribution. Sample contributors may be related according to a pedigree.

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4.62 score 2 stars 21 scripts 604 downloads

ibdsegments - Identity by Descent Probability in Pedigrees

Identity by Descent (IBD) distributions in pedigrees. A Hidden Markov Model is used to compute identity coefficients, simulate IBD segments and to derive the distribution of total IBD sharing and segment count across chromosomes. The methods are applied in Kruijver (2025) <doi:10.3390/genes16050492>. The probability that the total IBD sharing is zero can be computed using the method of Donnelly (1983) <doi:10.1016/0040-5809(83)90004-7>.

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cpp

3.40 score 5 stars 130 downloads

forensim - Interpretation of Forensic DNA Mixtures

Statistical methods and simulation tools for the interpretation of forensic DNA mixtures. The methods implemented are described in Haned et al. (2011) <doi:10.1111/j.1556-4029.2010.01550.x>, Haned et al. (2012) <doi:10.1016/j.fsigen.2012.11.002> and Gill & Haned (2013) <doi:10.1016/j.fsigen.2012.08.008>.

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2.78 score 12 scripts 592 downloads

disclapmix2 - Mixtures of Discrete Laplace Distributions using Numerical Optimisation

Fit a mixture of Discrete Laplace distributions using plain numerical optimisation. This package has similar applications as the 'disclapmix' package that uses an EM algorithm.

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cpp

2.70 score 2 scripts 222 downloads

forensicpopdata - Allele Frequency Data for Human Genetic Markers

Provides allele frequency data for Short Tandem Repeat human genetic markers commonly used in forensic genetics for human identification and kinship analysis. Includes published population frequency data from the US National Institute of Standards and Technology, Federal Bureau of Investigation and the UK government.

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2.70 score 161 downloads